Center for Advanced Training in Hemophilia and Inhibitor Management (CATHIM) Workshop

The Nationwide Children’s Hospital Pediatric Hematology Division along with its affiliated institution, The Ohio State University College of Medicine, are jointly hosting an upcoming educational workshop, the Center for Advanced Training in Hemophilia and Inhibitor Management (CATHIM), focused on the clinical care of patients with hemophilia and inhibitors.

CATHIM is a focused, hands-on workshop with the goal of inciting interest in the field of coagulation medicine in the attendees, and to fill a gap that exists in many current hematology training programs with respect to managing patients with complex hemostatic disorders. The target audience is physicians in adult and pediatric hematology fellowships, trainees in hematology and immunology, and Advance Practice Nurses.

The workshop will be held Friday, October 20, 2017 – Sunday, October 22, 2017, in Columbus, Ohio. There are scholarships available to cover travel and/or hotel expenses for those individuals who may be eligible to apply.

3rd Annual Inhibitors to Factor VIII /IX Symposium

The Nationwide Children’s Hospital Pediatric Hematology Division along with its affiliated institution, The Ohio State University College of Medicine, are jointly hosting the third annual educational symposium, Inhibitors Symposium to Factor VIII Symposium, focused on hemophilia healthcare providers along with basic/translational scientists with interest in protein therapeutics, immunology, statistics and genetics with a special interest in Hemophilia.

Registration is open to hemophilia providers and researchers, and covers all course materials, group meals and breaks.

Scholarships are available for participants and cover transportation and one night’s accommodations.
The workshop will be held Monday, October 23, 2017, in Columbus, Ohio.

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Conference Objectives

CATHIM WORKSHOP

  • Understand the clinical scenarios in which inhibitors maybe initially detected

  • Describe the age-specific patterns of bleeding that hemophilia patients with inhibitors may experience
  • Understand the treatment options available to treat hemophilia patients with inhibitors
  • Discuss the role of factor concentrates on inhibitor development
  • Assess the hemophilia patient-specific risks for inhibitor development
  • Understand the treatment options available to treat hemophilia patients with inhibitors
  • Describe the regimens used to induce immune tolerance in hemophilia patient with inhibitors and the outcomes with these regimens
  • Describe the options, alternatives, risks and benefits of the different modalities for venous access in patients with hemophilia
  • Understand the role of the clinical laboratory in the evaluation and management of patients with hemostatic disorders
  • Appreciate the pathobiology of hemophilic arthropathy
  • Gain confidence in the clinical management of elective surgery in hemophilia patients with inhibitors
  • Gain experience in the practical application of knowledge through case studies and simulation training in hemophilia care
  • Describe basic tenants of quality improvement methodology
  • Describe the use of point-of-care ultrasound in the assessment of hemophilic joints

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

INHIBITORS SYMPOSIUM

  • Analyze the Role of Genomic Investigation in Rare Conditions

  • Examine the role of the My Life Our Future Biorepository in Inhibitor Research

  • Discuss the role of Major Histocompatibility Proteins in the Immune Response

  • Investigate the Role of Glycan’s in the Early Immune Response

  • Compare Novel Hemophilia Therapeutics

  • Describe Laboratory Monitoring Options for Novel Therapeutics

  • Evaluate the Role of Oral Tolerance Strategies at Preventing Inhibitor Development

  • Analyze the Role of Particle Loading in Inhibitor Treatment

Frequently Asked Questions

CATHIM WORKSHOP

 

 

INHIBITORS SYMPOSIUM

Planning Committee & Faculty

Amy Dunn, MD
Amy Dunn, MDColumbus, OH
CATHIM/Inhibitors Symposium Co-Director
Nationwide Children’s Hospital
Riten Kumar, MD
Riten Kumar, MDColumbus, OH
CATHIM/Inhibitors Symposium Co-Director
Nationwide Children’s Hospital

CATHIM WORKSHOP

INHIBITORS SYMPOSIUM

Nihal Bakeer, MD
Nihal Bakeer, MDIndianapolis, IN
Mike Fetzer
Mike FetzerColumbus, OH
Rebecca Kruse- Jarres, MD
Rebecca Kruse- Jarres, MDSeattle, WA
Alice Ma, MD
Alice Ma, MDChapel Hill, NC
Shannon L. Meeks, MD
Shannon L. Meeks, MDAtlanta, GA
Rajiv Pruthi, MBBS
Rajiv Pruthi, MBBSRochester, MN
Mark Reding, MD
Mark Reding, MDMinneapolis, MN
Tammuella Singleton, MD
Tammuella Singleton, MDNew Orleans, LA
Bruno Steiner, PT, RMSK
Bruno Steiner, PT, RMSKSeattle, WA

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Roland Herzog, PhD
Roland Herzog, PhDGainesville, FL
Barbara Konkle, MD
Barbara Konkle, MDSeattle, WA
Wilbur Lam, MD, PhD
Wilbur Lam, MD, PhDAtlanta, GA
Shannon L. Meeks, MD
Shannon L. Meeks, MDAtlanta, GA
Kate Pratt, PhD
Kate Pratt, PhDBethesda, MD
Surbhi Saini, MD
Surbhi Saini, MDHershey, PA
Sean Stowell, MD, PhD
Sean Stowell, MD, PhDAtlanta, GA
Rick Wilson, PhD
Rick Wilson, PhDColumbus, OH

Program

CATHIM WORKSHOP

Welcome Reception

Friday, October 20, 2017; 06:30PM – 09:30PM

The Hilton

Symposium attendees are invited to join us for dinner at a special welcome reception on Friday evening.

07:00AM | Breakfast

08:00AM | Welcome & Introductions

Amy Dunn, MD (Columbus, OH)

08:15AM | Hemophilia Overview and Treatment (Including factor options, prophylaxis, adherence, etc.)

Alice Ma, MD (Chapel Hill, NC)

09:00AM | Introduction to Inhibitors (risk factors)

Riten Kumar, MD (Columbus, OH)

09:45AM | Break

10:00AM | Laboratory Evaluation of Inhibitors and Treatment (factor levels, Bethesda titers, Global hemostatic assays)

Rahiv Pruthi, MBBS (Rochester, MN)

10:45AM | Immunology and Immune Tolerance Therapy for Eradication of Inhibitors

Shannon Meeks, MD (Atlanta, GA)

11:30AM | Introduction to point of care ultrasound

Bruno Steiner, PT, RMSK (Seattle, WA) & Nihal Bakeer, MD (Indianapolis, IN)

12:15PM | Lunch 

01:00PM | Hemophilic Arthropathy (pathophysiology, radiologic, evaluation, interventions)

Amy Dunn, MD (Columbus, OH)

01:40PM | Clinical Breakout

  • Clinical Breakout: 6 groups of 5
  • Each participant can choose 2 of the 4 sessions to attend
  • Each session is 30 minutes with 15 minutes to switch sessions
  • Ultrasound groups will be groups of 5
  • Group 5 will stay in ultrasound from 1:40-2:40 p.m.
  • Group 6 will stay in ultrasound from 2:20-3:40 p.m.
  • Participants will have one ultrasound session and one break-out session or 2 break-out sessions

Group1-Dunn and Kruse-Jarres | The factor VIII molecule utilizing virtual reality platform

Group 2-Kumar and Pruthi | Practical Bethesda Assay

Group 3-Meeks and Pruthi | Practical Bethesda Assay

Group 4-Singleton and Reding | Hemophilia Jeopardy

Group5– Steiner and Bakeer | Ultrasound hands-on

03:40PM | Break

03:45PM | Introduction to Quality Improvement in Hemophilia

Mike Fetzer (Columbus, OH)

04:30PM | Wrap- up

Riten Kumar, MD (Columbus, OH)

06:30 | Dinner at Barley Brewing Company Followed by Highball Halloween Party

08:15AM | Breakfast

08:45AM | Venous Access and Other Pediatric Issues in Hemophilia

Tammuella Singleton, MD (New Orleans, LA)

09:30AM | Acquired Hemophilia

Rebecca Kruse- Jarres, MD (Seattle, WA)

10:15AM | Break

10:30AM | Treatment and Prevention of Bleeds in Patients with Inhibitors

Mark Reding, MD (Minneapolis, MN)

10:45PM | Clinical Breakout

  • Emergency Management of Bleeding and hands-on ultrasound training 6 groups of 2-3 participants.
  • Each ultrasound group will spend 60 minutes and each small group will spend 20 minutes per session.
  • Ultrasound groups of 5 participants
  • 10:45-11:45 a.m.
  • 11:45 a.m.-12:45 p.m.
  • Each person would get one hour for ultrasound and 3 small groups or 6 small groups

Group 1 – Dunn | Joint bleeding

Group 2 – Kruse-Jarres | Compartment syndrome

Group 3 – Kumar | Pseudotumor

Group 4 – Ma | Cardiac surgery

Group 5 – Meeks | PAC placement

Group 6 – Pruthi | Iliopsoas bleed

Group 7 –  Reding | GI bleeding

Group 8 – Singleton | Intracranial hemorrhage

Ultrasound group – Steiner and Bakeer

 12:45PM | Wrap-up and evaluations

Amy Dunn, MD (Columbus, OH)

01:00PM | Lunch & Departures

 

 

 

 

 

 

 

 

 

INHIBITORS SYMPOSIUM

Welcome Reception & Dinner

Sunday, October 22, 2017; 7:00PM – 9:00PM

Martini Modern Italian

445 N. High Street, Columbus, OH 43215

08:00AM | Continental Breakfast

08:30AM | Welcome & Introductions

Amy Dunn, MD (Columbus, OH)
Symposium Co- Chair, Nationwide Children’s Hospital

08:40AM | The Role of Genomic Investigation in Rare Conditions

Rick Wilson, PhD (Columbus, OH)
Nationwide Children’s Hospital

09:20AM | The Role of My Life our Future In Inhibitor Research

Barbara Konkle, MD (Seattle, WA)
University of Washington School of Medicine

10:00AM | Break

10:15AM | The Role of the Major Histocompatibility Complex in Inhibitor Development

Surbhi Saini, MD (Hershey, PA)
Penn State Children’s Hospital

10:55AM | The Role Of Glycans In The Early Immune Response

Sean Stowell, MD, PhD (Atlanta, GA)
Emory University School of Medicine

11:35AM | A Review of Novel Therapeutic Agents

Riten Kumar, MD (Columbus, OH)
Symposium Co- Chair, Nationwide Children’s Hospital

12:15PM | Lunch 

01:00PM | Laboratory Monitoring of New Hemophilia Agents

Shannon L. Meeks, MD (Atlanta, GA)
Emory University School of Medicine

01:40PM | Engineering less Immunogenic and Antigenic FVIII proteins

Kate Pratt, PhD (Bethesda, MD)
Uniformed Services University of the Health Sciences

02:20PM | Break

02:35PM | Plant Based Oral Tolerance Strategies

Roland Herzog, PhD (Gainesville, FL)
University of Florida

03:15PM | Particle Loading

Wilbur Lam, MD, PhD (Atlanta, GA)
Georgia Institute of Technology and Emory University School of Medicine

03:55PM | Wrap- up/ evaluations

04:10PM | Discussion time and Departures

Educational Grants

CATHIM WORKSHOP

 

 

 

 

 

 

 

 

 

INHIBITORS SYMPOSIUM

Registration/ Scholarships

CATHIM WORKSHOP

THE CATHIM WORKSHOP IS FULL.  No more applications are being accepted for the 2017 Program.

If interested in adding your name to the mailing list for future Nationwide Children’s Hospital Hemophilia Conferences or CATHIM Meetings, please email Connie Hieatt at connie.hieatt@nationwidechildrens.org

 

 

 

 

 

 

 

 

 

 

INHIBITORS SYMPOSIUM

FREE Registration, in the form of a scholarship, is available to hemophilia providers.  Scholarships cover all course materials, group meals and breaks. For registration information, all Industry Participants and Sponsor Representatives should email Inhibitors@nationwidechildrens.org

Scholarships are available for participants and cover transportation and 1 night’s hotel accommodations.

Before a registration can be confirmed and travel and hotel arranged, a scholarship application needs to be submitted by the participant and must be approved by the directors of the meeting.

Submit the following two (2) documents to complete your scholarship information to Inhibitors@nationwidechildrens.org. (1) CV; (2) a brief (500 word) personal statement explaining why you would like to attend Inhibitors to Factor VIII Symposium. Selected participants will receive a confirmation if your scholarship is approved. If you do not qualify for attendance, your registration will be cancelled and you will be notified. If approved, you will receive flight and hotel confirmations to attend the meeting.

Registration is limited and is on a first come, first serve basis. Registration is restricted to four (4) fellows per fellowship program.

The first function begins with an optional Welcome Reception and Dinner on Sunday, October 22nd, at 6:30 p.m. The last function ends at 4:10 p.m. on Monday, October 23rd. A complete tentative agenda may be found on the Agenda tab of this website.

Subject line of email must read: Inhibitors Scholarship Submission

Travel & Accommodations

Check out the Hotel

Hilton Columbus Downtown

Participants for CATHIM Workshop and the Inhibitors Symposium will stay at the Hilton Downtown Columbus Hotel. Once scholarships are awarded, rooms will be reserved by the Nationwide Children's Hospital Events Coordinator. CATHIM Workshop and Inhibitors Symposium participants should NOT make their own reservation. Shuttle service will be provided from the hotel to the Nationwide Children's Hospital Education Center for the Inhibitors Symposium.

Check out the Hotel

Hilton Columbus Downtown offers a contemporary presence in the eclectic hub of Columbus. Explore our $1 million art collection featuring original works from more than 100 area artists. Our Columbus, OH hotel is within walking distance to over 300 dining and entertainment venues. Take our unique spiral staircase for dining and fitness options. Unwind over dinner and drinks at our Gallerie Bar.

The CATHIM Workshop will be held at the Hilton Downtown Columbus. Address: 401 N. High St., Columbus, OH 43215.

The Inhibitors Symposium sessions will be held at the Nationwide Children’s Hospital, Education Center, Stecker Auditorium at 700 Children’s Dr. Columbus,  OH 43205.  Parking is not available at the hospital  for meeting participants. Shuttle services will be provided daily from the hotel to the hospital.

Getting to Columbus

John Glenn Columbus International Airport, located just 15 minutes from the Hilton, is served by 10 airlines and their regional affiliates, providing 350 daily arrivals and departures serving 35 destinations on a non-stop basis and hundreds of additional cities on a direct or connecting basis. Major carriers include AirTran, Air Canada Express, American, Delta, Southwest, United and US Airways. All ground transportation may be accessed via the terminal walkway or baggage claim levels.

From John Glenn Columbus International Airport, the best mode of transportation is via taxi readily available 24-hours a day at the cab stand outside baggage claim. The 15-minute ride should run around $25 inclusive. The hotel does not have an airport shuttle.

Columbus also offers Uber car services as well as a number of private scheduled sedan services including Cardinal Transportation.

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